| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| M ENZALUTAMIDE (is an active metabolite)
| ENZALUTAMIDE | ANTINEOPLASTIC | - | Cmax 28.2 MICROMOLAR VD 288 LITER (EQN) PPB 95 PERCENT Cl 1.02 LITER / HOUR HT 196 HOUR | ANDROGEN RECEPTOR (AR) | Androgen receptor UNIPROT P10275 AR more at DrugCentral | EMA | |||
