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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BUSULFAN

BUSULFAN


ATC L01AB01

ANTINEOPLASTIC
ALKYLATING AGENTS
IMMUNOSUPPRESSIVE AGENTS
MYELOABLATIVE AGONISTS
PRODUCES REACTIVE CARBONIUM IONS THAT CAN ALKYLATE DNA

ORAL INJECTION

Cmax 4.9 MICROMOLAR

VD 41.6 LITER (65 KILOGRAM)

PPB 32.4 PERCENT

Cl 9.8 LITER / HOUR (65 KILOGRAM)

HT 3.4 HOUR

SOLUBILITY 0.1 GRAM / LITER

DNA

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ChEMBL
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