Cheminformatic Tools and Databases for Pharmacology

session 88986 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CABAZITAXEL

CABAZITAXEL


ATC L01CD04

ANTINEOPLASTIC
MICROTUBULE INHIBITOR
HORMONE-REFRACTORY METASTATIC PROSTATE CANCER
TAXANE
INHIBITION OF MITOTIC AND INTERPHASE CELLULAR FUNCTION

INTRAVENOUS INJECTION IV

Cmax 270 NANOMOLAR (25 MILLIGRAM / M2)

VD 4864 LITER

PPB 91 PERCENT

Cl 48.5 LITER / HOUR

HT 95 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

MICROTUBULE
BINDS TO TUBULIN AND PROMOTES ITS ASSEMBLY INTO MICROTUBULES WHILE SIMULTANEOUSLY INHIBITING DISASSEMBLY

TUBULIN INHIBITOR CHEMBL2095182 TUBULIN P04350 TUBULIN BETA-4A CHAIN HOMO SAPIENS STRUCTURALANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |