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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
FENOFIBRIC ACID (is an active metabolite)

FENOFIBRIC ACID
CHOLINE FENOFIBRATE


ATC C10AB05
ATC C10BA03
ATC C10BA12
ATC C10BA09
ATC C10BA04

CARDIOVASCULAR
HYPOCHOLESTEROLEMIC
HYPOLIPIDEMIC
PEROXISOME PROLIFERATOR RECEPTOR ALPHA (PPAR ALPHA) AGONIST

ORAL

Tmax 5 HOUR

F 81 PERCENT

PPB 99 PERCENT

HT 20 HOUR

SOLUBILITY INSOLUBLE IN WATER

PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA

PDB 7BQ0 (X-RAY STRUCTURE OF HUMAN PPARALPHA LIGAND BINDING DOMAIN-FENOFIBRIC ACID-SRC1 COACTIVATOR PEPTIDE CO-CRYSTALS OBTAINED BY DELIPIDATION AND CO-CRYSTALLIZATION)

LIGAND CODE = F5A (link to the list of PDB complexes)

Download experimental 3D coordinates of F5A with added hydrogens

Peroxisome proliferator-activated receptor alpha UNIPROT Q07869 PPARA

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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