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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CARGLUMIC ACID

CARGLUMIC ACID


ATC A16AA05

HYPERAMMONAEMIA
CARBAMOYL PHOSPHATE SYNTHETASE 1 (CPS 1) AGONIST IN LIVER MITOCHONDRIA
DEFICIENCY OF THE HEPATIC ENZYME N-ACETYLGLUTAMATE SYNTHASE (NAGS)
STRUCTURAL ANALOGUE OF N-ACETYLGLUTAMATE (NAG)

ORAL

VD 2657 LITER

Cl 342 LITER / HOUR

HT 5.6 HOUR

SOLUBILITY SOLUBLE IN BOILING WATER AND SLIGHTLY SOLUBLE IN COLD WATER

CARBAMOYL PHOSPHATE SYNTHETASE 1 (CPS 1)

CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL POSITIVE ALLOSTERIC MODULATOR CHEMBL2362990 CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL P31327 CARBAMOYL-PHOSPHATE SYNTHASE [AMMONIA], MITOCHONDRIAL HOMO SAPIENS ENZYME LIGASEANSM (in French)

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