Cheminformatic Tools and Databases for Pharmacology

session 75149 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DALFAMPRIDINE

DALFAMPRIDINE


ATC N07XX07

NERVOUS SYSTEM
MULTIPLE SCLEROSIS
BROAD SPECTRUM POTASSIUM ION CHANNELS INHIBITOR (KV)
INDICATED TO IMPROVE WALKING IN PATIENTS WITH MULTIPLE SCLEROSIS (MS)

ORAL

Cmax 0.318 MICROMOLAR (10 MILLIGRAM)

F 96 PERCENT

VD 169 LITER (65 KILOGRAM)

PPB 98 PERCENT

Cl 20 LITER / HOUR (EQN)

HT 5.8 HOUR

SOLUBILITY SOLUBLE IN WATER

SHAKER
KCNA

Voltage-gated potassium channel UNIPROT O43525 KCNQ3

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |