| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ROMIDEPSIN
| ROMIDEPSIN | ANTINEOPLASTIC | INTRAVENOUS | Cmax 0.698 MICROMOLAR (14 MILLIGRAM / M2) VD 78 LITER (65 KILOGRAM) PPB 93 PERCENT Cl 28.8 LITER / HOUR (65 KILOGRAM) HT 3 HOUR (14 MILLIGRAM / M2) | HISTONE DEACETYLASE (IC50 NANOMOLAR RANGE) | Histone deacetylase UNIPROT O15379 HDAC3 more at DrugCentral | EMA | |||
