Cheminformatic Tools and Databases for Pharmacology

session 74818 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PAZOPANIB

PAZOPANIB


ATC L01XE11

ANTINEOPLASTIC
PROTEIN KINASE INHIBITORS
RENAL CELL CARCINOMA
SOFT TISSUE SARCOMA

ORAL

Cmax 132.9 MICROMOLAR (800 MILLIGRAM)

Tmax 3 HOUR

PPB 99 PERCENT

HT 30.9 HOUR (800 MILLIGRAM)

SOLUBILITY PRACTICALLY INSOLUBLE ABOVE PH 4 IN WATER

VEGFR-1
VEGFR-2
VEGFR-3
PDGFR-ALPHA
PDGRF-BETA
FGFR-1
FGFR-3
KIT
ITK
LCK
TRANSMEMBRANE GLYCOPROTEIN RECEPTOR TYROSINE KINASE (C-FMS)

TYROSINE-PROTEIN KINASE LCK INHIBITOR CHEMBL258 TYROSINE-PROTEIN KINASE LCK P06239 TYROSINE-PROTEIN KINASE LCK HOMO SAPIENS ENZYME KINASE PROTEIN KINASE TK SRCANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |