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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TELAVANCIN

TELAVANCIN


ATC J01XA03

ANTIINFECTIVE
LIPOGLYCOPEPTIDE ANTIBACTERIALS
SKIN INFECTION
GRAM-POSITIVE BACTERIA
SYNTHETIC DERIVATIVE OF VANCOMYCIN
INHIBITS BACTERIAL CELL WALL SYNTHESIS BY INTERFERING WITH THE POLYMERIZATION AND CROSS-LINKING OF PEPTIDOGLYCAN

INTRAVENOUS INJECTION

Cmax 57.4 MICROMOLAR (10 MILLIGRAM / KILOGRAM)

VD 9.4 LITER (65 KILOGRAM)

PPB 90 PERCENT

Cl 0.9 LITER / HOUR (65 KILOGRAM)

HT 8 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

CELL OUTER MEMBRANE INHIBITOR CHEMBL2364032 CELL OUTER MEMBRANE BACTERIAANSM (in French)

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