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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BEPOTASTINE

BEPOTASTINE

ANTI-ALLERGIC
ANTIHISTAMINES
HISTAMINE H1 ANTAGONIST
CONJUNCTIVITIS
ITCHING
SENSORY

OPHTHALMIC

Cmax 13.14 NANOMOLAR (1.5 PERCENT)

Tmax 1.5 HOUR

PPB 55 PERCENT

HISTAMINE H1 RECEPTOR

HISTAMINE H1 RECEPTOR ANTAGONIST CHEMBL231 HISTAMINE H1 RECEPTOR P35367 HISTAMINE H1 RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR HISTAMINE RECEPTORANSM (in French)

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