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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
VIGABATRIN

VIGABATRIN


ATC N03AG04

NERVOUS SYSTEM
ANTIEPILEPTICS
ANTICONVULSANTS
REFRACTORY COMPLEX PARTIAL SEIZURES IN ADULTS
IRREVERSIBLE INHIBITOR OF GAMMA-AMINOBUTYRIC ACID TRANSAMINASE (GABA-T)

ORAL

VD 71.5 LITER (65 KILOGRAM)

PPB 0 PERCENT

Cl 6.6 LITER / HOUR (EQN)

HT 7.5 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

4-AMINOBUTYRATE AMINOTRANSFERASE MITOCHONDRIAL

GAMMA-AMINO-N-BUTYRATE TRANSAMINASE INHIBITOR CHEMBL2044 GAMMA-AMINO-N-BUTYRATE TRANSAMINASE P80404 4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL HOMO SAPIENS ENZYME TRANSFERASEANSM (in French)

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