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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| VIGABATRIN
| VIGABATRIN | NERVOUS SYSTEM | ORAL | VD 71.5 LITER (65 KILOGRAM) PPB 0 PERCENT Cl 6.6 LITER / HOUR (EQN) HT 7.5 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | 4-AMINOBUTYRATE AMINOTRANSFERASE MITOCHONDRIAL | 4-aminobutyrate aminotransferase, mitochondrial UNIPROT P80404 ABAT more at DrugCentral | EMA | |||
