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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PITAVASTATIN

PITAVASTATIN


ATC C10AA08

HMG-COA REDUCTASE INHIBITOR
ANTIHYPERLIPIDEMIC
CARDIOVASCULAR
LIPID-LOWERING AGENT

ORAL

F 51 PERCENT

VD 148 LITER

PPB 99 PERCENT

Cl 8.5 LITER / HOUR (EQN)

HT 12 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER

3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE (HMG-COA)

HMG-COA REDUCTASE INHIBITOR CHEMBL402 HMG-COA REDUCTASE P04035 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE HOMO SAPIENS ENZYME REDUCTASEANSM (in French)

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