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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BESIFLOXACIN

BESIFLOXACIN


ATC S01AE08

ANTIBIOTIC
ANTIBACTERIAL
ANTI-INFECTIVES
FOURTH-GENERATION FLUOROQUINOLONE ANTIBIOTIC
ANTIINFECTIVES
DNA GYRASE INHIBITOR
TOPOISOMERASE IV INHIBITOR

OPHTHALMIC

Cmax 1.09 NANOMOLAR

HT 7 HOUR

DNA GYRASE
TOPOISOMERASE IV

Topoisomerase IV UNIPROT P0AFI2 parC -- DNA gyrase UNIPROT P0AES4 gyrA

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