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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TOLVAPTAN
| TOLVAPTAN | DIURETIC | ORAL | VD 195 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 15.6 LITER / HOUR (65 KILOGRAM) HT 12 HOUR | ARGININE VASOPRESSIN RECEPTOR 2 | Vasopressin V2 receptor UNIPROT P30518 AVPR2 more at DrugCentral | EMA | |||
