Cheminformatic Tools and Databases for Pharmacology

session 68297 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
FOSPROPOFOL DISCONTINUED (has an active metabolite)

FOSPROPOFOL


ATC N01AX10

NERVOUS SYSTEM
SEDATIVE
HYPNOTIC
ANESTHESIC
METABOLIZED BY ALKALINE PHOSPHATASES INTO PROPOFOL

INTRAVENOUS

Cmax 732.6 MICROMOLAR (18 MILLIGRAM/KG)

VD 21.4 LITER (65 KILOGRAM)

PPB 98 PERCENT

Cl 18.2 LITER / HOUR (65 KILOGRAM)

HT 0.81 HOUR (18 MILLIGRAM/KG)

SOLUBILITY WATER SOLUBLE PRODRUG OF PROPOFOL

GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT ALPHA-1 (GABA(A))
BETA-ADRENOCEPTOR (BETA-AR) (PMID21793316)

GABA-A RECEPTOR O14764 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT DELTA HOMO SAPIENS ION CHANNEL LGIC GABAAANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |