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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PLICAMYCIN DISCONTINUED
| PLICAMYCIN | NATURAL MOLECULE (link) ANTINEOPLASTIC | INJECTION | DNA PDB 6VGG (CRYSTAL STRUCTURE OF THE DNA BINDING DOMAINS OF HUMAN TRANSCRIPTION FACTOR ERG, HUMAN RUNX2 BOUND TO CORE BINDING FACTOR BETA (CBFB), AND MITHRAMYCIN, IN COMPLEX WITH 16MER DNA CAGAGGATGTGGCTTC) LIGAND CODE = QWP (link to the list of PDB complexes) Download experimental 3D coordinates of QWP with added hydrogens | Unknown more at DrugCentral | EMA | ||||
