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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CLEVIDIPINE

CLEVIDIPINE


ATC C08CA16

CARDIOVASCULAR
VASODILATOR
ANTIHYPERTENSIVE
DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKER
REDUCTION OF BLOOD PRESSURE
THE CARBOXYLIC ACID METABOLITE IS INACTIVE AS AN ANTIHYPERTENSIVE

INTRAVENOUS

VD 11 LITER (65 KILOGRAM)

PPB 99.5 PERCENT

Cl 30.4 LITER / HOUR (EQN)

HT 0.25 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

L-TYPE CALCIUM CHANNEL BLOCKER

VOLTAGE-GATED L-TYPE CALCIUM CHANNEL BLOCKER CHEMBL2095229 VOLTAGE-GATED L-TYPE CALCIUM CHANNEL O60840 VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1F HOMO SAPIENS ION CHANNEL VGC VG CAANSM (in French)

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