Cheminformatic Tools and Databases for Pharmacology

session 49027 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NEPAFENAC (has an active metabolite)

NEPAFENAC


ATC S01BC10

SENSORY
ANTIINFLAMMATORY
NONSTEROIDAL ANTI-INFLAMMATORY (NSAID) PRODRUG
TREATMENT OF PAIN AND INFLAMMATION ASSOCIATED WITH CATARACT SURGERY
CONVERTED BY OCULAR TISSUE HYDROLASES TO AMFENAC
INHIBITOR THE ACTION OF PROSTAGLANDIN H SYNTHASE (CYCLOOXYGENASE)

OPHTHALMIC

Cmax 1.22 NANOMOLAR

Tmax 0.5 HOUR

PROSTAGLANDIN H SYNTHASE (CYCLOOXYGENASE)

Prostaglandin G,H synthase 2 UNIPROT P35354 PTGS2 -- Prostaglandin G,H synthase 1 UNIPROT P23219 PTGS1

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |