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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
GANIRELIX

GANIRELIX


ATC H01CC01

HORMONES
GONADOTROPIN-RELEASING HORMONE ANTAGONIST (GNRH ANTAGONIST)
STIMULATES THE SYNTHESIS AND SECRETION OF LUTEINIZING HORMONE (LH) AND FOLLICLE-STIMULATING HORMONE (FSH)

INJECTION

Cmax 7.14 NANOMOLAR

F 91.1 PERCENT (250 MICROGRAM)

VD 43.7 LITER

PPB 81.9 PERCENT

Cl 3.3 LITER / HOUR

HT 16.2 HOUR

GONADOTROPIN-RELEASING HORMONE RECEPTOR

GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONIST CHEMBL1855 GONADOTROPIN-RELEASING HORMONE RECEPTOR P30968 GONADOTROPIN-RELEASING HORMONE RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE GNRH RECEPTORANSM (in French)

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