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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CHLORPROMAZINE
| CHLORPROMAZINE | NERVOUS SYSTEM | ORAL INJECTION RECTAL | F 21 PERCENT VD 1215 LITER PPB 94.4 PERCENT Cl 76.6 LITER / HOUR HT 11.05 HOUR | DOPAMINE RECEPTOR PDB 5LG3 (X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH CHLORPROMAZINE) LIGAND CODE = Z80 (link to the list of PDB complexes) Download experimental 3D coordinates of Z80 with added hydrogens | D(2) dopamine receptor UNIPROT P14416 DRD2 more at DrugCentral | EMA | |||
