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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CHLORPROMAZINE

CHLORPROMAZINE


ATC N05AA01

NERVOUS SYSTEM
ANTIEMETICS
ANTIPSYCHOTIC AGENTS
DOPAMINE ANTAGONISTS
PHENOTHIAZINES
SEDATIVES

ORAL INJECTION RECTAL

F 21 PERCENT

VD 1215 LITER

PPB 94.4 PERCENT

Cl 76.6 LITER / HOUR

HT 11.05 HOUR

DOPAMINE RECEPTOR

PDB 5LG3 (X-RAY STRUCTURE OF A PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI (ELIC) IN COMPLEX WITH CHLORPROMAZINE)

LIGAND CODE = Z80 (link to the list of PDB complexes)

Download experimental 3D coordinates of Z80 with added hydrogens

D2-LIKE DOPAMINE RECEPTOR ANTAGONIST CHEMBL2331075 D2-LIKE DOPAMINE RECEPTOR P14416 D(2) DOPAMINE RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR DOPAMINE RECEPTORANSM (in French)

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