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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NALMEFENE DISCONTINUED

NALMEFENE


ATC N07BB05

NERVOUS SYSTEM
NARCOTIC OPIOID ANTAGONIST
PREVENTS OR REVERSES THE EFFECTS OF OPIOIDS, INCLUDING RESPIRATORY DEPRESSION, SEDATION, AND HYPOTENSION

INTRAMUSCULAR INTRAVENOUS SUBCUTANEOUS

F 99 PERCENT

VD 559 LITER (65 KILOGRAM)

PPB 45 PERCENT

Cl 52 LITER / HOUR (65 KILOGRAM)

HT 10.8 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER UP TO 130 MILLIGRAM / MILLILITER

OPIOID RECEPTOR

OPIOID RECEPTORS MU/KAPPA/DELTA ANTAGONIST CHEMBL2095181 OPIOID RECEPTORS MU/KAPPA/DELTA P35372 MU-TYPE OPIOID RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE OPIOID RECEPTORANSM (in French)

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