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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| RESERPINE DISCONTINUED
| RESERPINE | NATURAL MOLECULE (link)
CARDIOVASCULAR | ORAL INJECTION | Cmax 1.8 NANOMOLAR Tmax 2.5 HOUR F 50 PERCENT PPB 95 PERCENT HT 200 HOUR SOLUBILITY INSOLUBLE IN WATER | PDB 8JTC (HUMAN VMAT2 COMPLEX WITH RESERPINE) LIGAND CODE = YHR (link to the list of PDB complexes) Download experimental 3D coordinates of YHR with added hydrogens | Synaptic vesicular amine transporter UNIPROT Q05940 SLC18A2 more at DrugCentral | EMA | |||
