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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
HISTRELIN

HISTRELIN


ATC H01CA03
ATC L02AE05

GONADOTROPIN RELEASING HORMONE (GNRH) AGONIST
HORMONES
TREATMENT OF ADVANCED PROSTATE CANCER INHIBITOR OF GONADOTROPIN SECRETION
TRANSIENT INCREASE IN CONCENTRATION OF GONADAL STEROIDS (TESTOSTERONE AND DIHYDROTESTOSTERONE IN MALES)
TREATMENT OF PRECOCIOUS PUBERTY

INJECTION SUBCUTANEOUS

Cmax 0.83 NANOMOLAR

F 92 PERCENT

VD 58.4 LITER

PPB 70.5 PERCENT

Cl 10.7 LITER / HOUR

HT 3.92 HOUR

GONADOTROPIN-RELEASING HORMONE RECEPTOR

GONADOTROPIN-RELEASING HORMONE RECEPTOR AGONIST CHEMBL1855 GONADOTROPIN-RELEASING HORMONE RECEPTOR P30968 GONADOTROPIN-RELEASING HORMONE RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE GNRH RECEPTORANSM (in French)

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