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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ACRIVASTINE DISCONTINUED

ACRIVASTINE


ATC R06AX18

RESPIRATORY
ANTIHISTAMINE
HISTAMINE H1-RECEPTOR ANTAGONIST
TREATMENT OF CHRONIC URTICARIA AND ALLERGIC RHINITIS

ORAL

Cmax 652 NANOMOLAR

Tmax 1.14 HOUR

VD 29.9 LITER (65 KILOGRAM)

PPB 50 PERCENT

Cl 11.3 LITER / HOUR (65 KILOGRAM)

HT 1.9 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

HISTAMINE H1-RECEPTOR (PMID1715267)

HISTAMINE H1 RECEPTOR ANTAGONIST CHEMBL231 HISTAMINE H1 RECEPTOR P35367 HISTAMINE H1 RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR HISTAMINE RECEPTORANSM (in French)

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