MESALAMINE (is an active metabolite) | MESALAMINE | ATC A07EC02
METABOLISM ANTIINFLAMMATORY IT IS POSSIBLE THAT IT DIMINISHES INFLAMMATION BY BLOCKING PRODUCTION OF ARACHIDONIC ACID METABOLITES INHIBITOR OF CYCLOOXYGENASE MAINTENANCE OF REMISSION OF ULCERATIVE COLITIS | RECTAL ORAL | Cmax 17.6 MICROMOLAR Tmax 6 HOUR F 28 PERCENT VD 21.4 LITER (65 KILOGRAM) PPB 43 PERCENT Cl 36.2 LITER / HOUR (65 KILOGRAM) HT 1 HOUR | PROSTAGLANDIN G/H SYNTHASE 1 PROSTAGLANDIN G/H SYNTHASE 2 | Prostaglandin G,H synthase 2 UNIPROT P35354 PTGS2 -- Prostaglandin G,H synthase 1 UNIPROT P23219 PTGS1 more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |