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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DRONABINOL
| DRONABINOL | METABOLISM | ORAL | Cmax 25 NANOMOLAR F 92.5 PERCENT VD 650 LITER (65 KILOGRAM) PPB 97 PERCENT Cl 13 LITER / HOUR (65 KILOGRAM) HT 30.5 HOUR SOLUBILITY INSOLUBLE IN WATER | CANNABINOID RECEPTOR PDB 7M6M (FULL LENGTH ALPHA1 GLYCINE RECEPTOR IN PRESENCE OF 32UM TETRAHYDROCANNABINOL) LIGAND CODE = TCI (link to the list of PDB complexes) Download experimental 3D coordinates of TCI with added hydrogens | Cannabinoid receptor 1 UNIPROT P21554 CNR1 more at DrugCentral | EMA | |||
