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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CALCIFEDIOL

CALCIFEDIOLNATURAL MOLECULE (link)


ATC A11CC06
ATC H05BX05

METABOLISM
CA REGULATOR
ANTIHYPOCALCEMIC AGENTS

ORAL 25(OH)D-1ALPHA-HYDROXYLASE

PDB 1J78 (CRYSTALLOGRAPHIC ANALYSIS OF THE HUMAN VITAMIN D BINDING PROTEIN)

LIGAND CODE = VDY (link to the list of PDB complexes)

Download experimental 3D coordinates of VDY with added hydrogens

Vitamin D3 receptor UNIPROT P11473 VDR

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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