PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)
Primary Target and PDB code of Protein-Drug complex
PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)
Primary Target and PDB code of Protein-Drug complex
HORMONE VASOPRESSIN RECEPTOR AGONIST WITH TWICE THE SELECTIVITY FOR VASOPRESSIN V1 RECEPTORS VERSUS V2 RECEPTORS INDICATED TO IMPROVE KIDNEY FUNCTION IN ADULTS THE MAJOR ACTIVE METABOLITE IS LYSINE- VASOPRESSIN