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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ETHACRYNATE
| ETHACRYNATE ETHACRYNIC ACID | CARDIOVASCULAR | INJECTION ORAL | SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER (ETHACRYNATE SODIUM, THE SODIUM SALT OF ETHACRYNIC ACID, IS SOLUBLE IN WATER) | PDB 11GS (GLUTATHIONE S-TRANSFERASE COMPLEXED WITH ETHACRYNIC ACID-GLUTATHIONE CONJUGATE (FORM II)) LIGAND CODE = EAA (link to the list of PDB complexes) Download experimental 3D coordinates of EAA with added hydrogens | Solute carrier family 12 member 1 UNIPROT Q13621 SLC12A1 more at DrugCentral | EMA | |||
