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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| EQUILIN
| EQUILIN | HORMONES | ORAL INJECTION TOPICAL VAGINAL | Cmax 0.15 NANOMOLAR Tmax 5 HOUR HT 15 HOUR | ESTROGEN RECEPTOR (ER) ESTRADIOL 17-BETA-DEHYDROGENASE 1 PDB 1EQU (TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EQUILIN COMPLEXED WITH NADP+) LIGAND CODE = EQI (link to the list of PDB complexes) Download experimental 3D coordinates of EQI with added hydrogens | Estrogen receptor UNIPROT P03372 ESR1 -- Estrogen receptor beta UNIPROT Q92731 ESR2 more at DrugCentral | EMA | |||
