Cheminformatic Tools and Databases for Pharmacology

session 92621 - Total of 1 hits - Display   hits per page:

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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
KANAMYCIN DISCONTINUED

KANAMYCINNATURAL MOLECULE (link)


ATC J01GB04
ATC A07AA08
ATC S01AA24

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
PROTEIN SYNTHESIS INHIBITORS

ORAL INJECTION

VD 16.9 LITER (65 KILOGRAM)

PPB 1 PERCENT

Cl 5.4 LITER / HOUR (65 KILOGRAM)

HT 2.1 HOUR

AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB
KANAMYCIN NUCLEOTIDYLTRANSFERASE

PDB 4FEX (CRYSTAL STRUCTURE OF THE AMINOGLYCOSIDE PHOSPHOTRANSFERASE APH(3')-IA, WITH SUBSTRATE KANAMYCIN AND SMALL MOLECULE INHIBITOR TYRPHOSTIN AG1478)

LIGAND CODE = KAN (link to the list of PDB complexes)

Download experimental 3D coordinates of KAN with added hydrogens

BACTERIAL 70S RIBOSOME INHIBITOR CHEMBL2363135 BACTERIAL 70S RIBOSOME 16S RIBOSOMAL RNA BACTERIAANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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