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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
SOLIFENACIN

SOLIFENACIN


ATC G04BD08
ATC G04CA53

GENITO
ANTI-INCONTINENCE AGENTS
ANTISPASMODICS
MUSCARINIC ANTAGONISTS

ORAL

Cmax 173.7 NANOMOLAR (10 MILLIGRAM)

F 90 PERCENT

VD 600 LITER

PPB 98 PERCENT

Cl 7.3 LITER / HOUR (EQN)

HT 56.5 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

MUSCARINIC ACETYLCHOLINE RECEPTOR

MUSCARINIC ACETYLCHOLINE RECEPTOR M2 ANTAGONIST CHEMBL211 MUSCARINIC ACETYLCHOLINE RECEPTOR M2 P08172 MUSCARINIC ACETYLCHOLINE RECEPTOR M2 HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ACETYLCHOLINE RECEPTORANSM (in French)

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