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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DARIFENACIN

DARIFENACIN


ATC G04BD10

GENITO
ANTIINFLAMMATORY
MUSCARINIC ANTAGONISTS
URINARY ANTISPASMODICS

ORAL

Cmax 23.4 NANOMOLAR (15 MILLIGRAM)

F 19 PERCENT

VD 163 LITER

PPB 98 PERCENT

Cl 40 LITER / HOUR

HT 16 HOUR

MUSCARINIC ACETYLCHOLINE RECEPTOR M3

MUSCARINIC ACETYLCHOLINE RECEPTOR M2 ANTAGONIST CHEMBL211 MUSCARINIC ACETYLCHOLINE RECEPTOR M2 P08172 MUSCARINIC ACETYLCHOLINE RECEPTOR M2 HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ACETYLCHOLINE RECEPTORANSM (in French)

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