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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CASPOFUNGIN
| CASPOFUNGIN | ANTIINFECTIVES | INTRAVENOUS | VD 8.45 LITER (65 KILOGRAM) PPB 97 PERCENT Cl 0.72 LITER / HOUR HT 27 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | BETA-1,3-GLUCAN SYNTHASE | Beta-1,3-glucan synthase catalytic subunit 1 UNIPROT O13428 GSC1 -- 1,3-beta-glucan synthase catalytic subunit FksP UNIPROT Q4WLT4 more at DrugCentral | EMA | |||
