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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PHENYTOIN (is an active metabolite)
| PHENYTOIN | NERVOUS SYSTEM | ORAL INJECTION | Tmax 1.5 HOUR PPB 88 PERCENT HT 22 HOUR | VOLTAGE-DEPENDENT SODIUM CHANNEL | Sodium channel protein type 5 subunit alpha UNIPROT Q14524 SCN5A -- Sodium channel protein type 1 subunit alpha UNIPROT P35498 SCN1A more at DrugCentral | EMA | |||
