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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PROPANTHELINE DISCONTINUED
| PROPANTHELINE | METABOLISM | ORAL INJECTION | Cmax 3.5 MICROMOLAR (PMID760746) Tmax 1 HOUR Cl 79.2 LITER / HOUR HT 1.6 HOUR SOLUBILITY VERY SOLUBLE IN WATER | MUSCARINIC ACETYLCHOLINE RECEPTOR | Muscarinic acetylcholine receptor M1 UNIPROT P11229 CHRM1 -- Muscarinic acetylcholine receptor M2 UNIPROT P08172 CHRM2 more at DrugCentral | EMA | |||
