Cheminformatic Tools and Databases for Pharmacology

session 11353 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DELAVIRDINE DISCONTINUED

DELAVIRDINE


ATC J05AG02

ANTIINFECTIVES
NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR (NNRTI) OF HIV-1
ANTIVIRAL

ORAL

Cmax 35 MICROMOLAR (400 MILLIGRAM)

Tmax 1 HOUR

F 85 PERCENT

PPB 98 PERCENT

HT 5.8 HOUR (400 MILLIGRAM)

SOLUBILITY 0.81 MICROGRAM PER MILLILITER (PH=7.4)

NON-NUCLEOSIDE REVERSE TRANSCRIPTASE (IC50=38 NANOMOLAR)
GAG-POL POLYPROTEIN

PDB 1KLM (HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH BHAP U-90152)

LIGAND CODE = SPP (link to the list of PDB complexes)

Download experimental 3D coordinates of SPP with added hydrogens

GAG-POL POLYPROTEIN P03369 GAG-POL POLYPROTEIN HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 GROUP M SUBTYPE B (ISOLATE ARV2/SF2) UNCLASSIFIEDANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |