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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BALSALAZIDE (has an active metabolite)
| BALSALAZIDE | METABOLISM | ORAL | Cmax 1.42 MICROMOLAR (3 TIMES 750 MILLIGRAM) Tmax 0.8 HOUR PPB 99 PERCENT HT 1.9 HOUR (SINGLE DOSE) SOLUBILITY FREELY SOLUBLE IN WATER | PROSTAGLANDIN G/H SYNTHASE 1 PROSTAGLANDIN G/H SYNTHASE 2 BACTERIAL NADPH AZOREDUCTASE | Prostaglandin G,H synthase 2 UNIPROT P35354 PTGS2 -- Prostaglandin G,H synthase 1 UNIPROT P23219 PTGS1 more at DrugCentral | EMA | |||
