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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BALSALAZIDE (has an active metabolite)

BALSALAZIDE


ATC A07EC04

METABOLISM
ANTIULCERATIVE
ANTI-INFLAMMATORY AGENTS NON-STEROIDAL
GASTROINTESTINAL AGENTS
PROSTAGLANDIN G/H SYNTHASE INHIBITOR

ORAL

Cmax 1.42 MICROMOLAR (3 TIMES 750 MILLIGRAM)

Tmax 0.8 HOUR

PPB 99 PERCENT

HT 1.9 HOUR (SINGLE DOSE)

SOLUBILITY FREELY SOLUBLE IN WATER

PROSTAGLANDIN G/H SYNTHASE 1
PROSTAGLANDIN G/H SYNTHASE 2
BACTERIAL NADPH AZOREDUCTASE

ARACHIDONATE 5-LIPOXYGENASE INHIBITOR CHEMBL215 ARACHIDONATE 5-LIPOXYGENASE P09917 ARACHIDONATE 5-LIPOXYGENASE HOMO SAPIENS ENZYME REDUCTASEANSM (in French)

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