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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TOREMIFENE
| TOREMIFENE | ANTINEOPLASTIC | ORAL | VD 580 LITER PPB 99.5 PERCENT Cl 5 LITER / HOUR HT 120 HOUR SOLUBILITY 0.63 MILLIGRAM / MILLILITER | ESTROGEN RECEPTOR PDB 5JQ7 (CRYSTAL STRUCTURE OF EBOLA GLYCOPROTEIN IN COMPLEX WITH TOREMIFENE) LIGAND CODE = T0R (link to the list of PDB complexes) Download experimental 3D coordinates of T0R with added hydrogens | Estrogen receptor UNIPROT P03372 ESR1 more at DrugCentral | EMA | |||
