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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ROCURONIUM

ROCURONIUM


ATC M03AC09

MUSCULO-SKELETAL SYSTEM
NEUROMUSCULAR NONDEPOLARIZING AGENTS
BLOCKER
SKELETAL MUSCLE RELAXANTS
ANESTHESIA
CHOLINERGIC RECEPTOR

INJECTION

VD 16.2 LITER (65 KILOGRAM)

PPB 30 PERCENT

Cl 16.2 LITER / HOUR (65 KILOGRAM)

HT 1.4 HOUR

SOLUBILITY PARTITION COEFFICIENT IN N-OCTANOL/WATER IS 0.5 AT 20 DEGREE CELSIUS.

MUSCARINIC ACETYLCHOLINE RECEPTOR M2
NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2

MUSCLE-TYPE NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONIST CHEMBL2362997 MUSCLE-TYPE NICOTINIC ACETYLCHOLINE RECEPTOR P02708 ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA HOMO SAPIENS ION CHANNEL LGIC ACH CHRN ALPHAANSM (in French)

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