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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NAFARELIN

NAFARELIN


ATC H01CA02

HORMONES
TREATMENT OF CENTRAL PRECOCIOUS PUBERTY (CPP)
GONADOTROPIN-RELEASING HORMONE AGONIST

NASAL

Cmax 1.36 NANOMOLAR

Tmax 0.4 HOUR

F 2.8 PERCENT

PPB 80 PERCENT

HT 3 HOUR

GONADOTROPIN-RELEASING HORMONE RECEPTOR
GONADOTROPIN-RELEASING HORMONE II RECEPTOR

GONADOTROPIN-RELEASING HORMONE RECEPTOR AGONIST CHEMBL1855 GONADOTROPIN-RELEASING HORMONE RECEPTOR P30968 GONADOTROPIN-RELEASING HORMONE RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE GNRH RECEPTORANSM (in French)

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