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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
GOSERELIN

GOSERELIN


ATC L02AE03

PROSTATE CANCER (THERAPEUTIC)
ANTINEOPLASTIC
GONADOTROPIN RELEASING HORMONE (GNRH) AGONIST
INHIBITS PITUITARY GONADOTROPIN SECRETION

IMPLANTATION

Cmax 2.23 NANOMOLAR

VD 20.3 LITER

PPB 27.3 PERCENT

Cl 9.78 LITER / HOUR

HT 1.4 HOUR (EQN)

SOLUBILITY SOLUBLE IN WATER

LUTROPIN-CHORIOGONADOTROPIC HORMONE RECEPTOR

GONADOTROPIN-RELEASING HORMONE RECEPTOR AGONIST CHEMBL1855 GONADOTROPIN-RELEASING HORMONE RECEPTOR P30968 GONADOTROPIN-RELEASING HORMONE RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE GNRH RECEPTORANSM (in French)

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