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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DOXAZOSIN

DOXAZOSIN


ATC C02CA04

CARDIOVASCULAR
ADRENOCEPTOR (ALPHA1) ANTAGONIST
ANTIHYPERTENSIVE
VASODILATOR AGENTS
TREATMENT OF PROSTATIC HYPERPLASIA (BPH)

ORAL

Cmax 57 NANOMOLAR (8 MILLIGRAM)

F 59 PERCENT

VD 84.5 LITER (65 KILOGRAM)

PPB 98 PERCENT

Cl 6.24 LITER / HOUR (65 KILOGRAM)

HT 17 HOUR

ALPHA-1 ADRENERGIC RECEPTOR

ADRENERGIC RECEPTOR ALPHA-1 ANTAGONIST CHEMBL2094251 ADRENERGIC RECEPTOR ALPHA-1 P25100 ALPHA-1D ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTORANSM (in French)

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Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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