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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NITROFURANTOIN

NITROFURANTOIN


ATC J01XE01
ATC J01XE51

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL
REDUCES BY BACTERIAL FLAVOPROTEINS TO REACTIVE INTERMEDIATES
ALTER BACTERIAL RIBOSOMAL PROTEINS

ORAL INJECTION

Cmax 3.67 MICROMOLAR

Tmax 2.15 HOUR (PMID18429968)

VD 37 LITER (65 KILOGRAM)

PPB 83 PERCENT

Cl 37.8 LITER / HOUR (65 KILOGRAM)

HT 0.97 HOUR

RIBOSOME

DNA INHIBITOR CHEMBL2364041 DNA BACTERIAANSM (in French)

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Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
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