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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
OCTREOTIDE

OCTREOTIDE


ATC H01CB02

HORMONES
HORMONE REPLACEMENT AGENTS
SOMATOSTATIN MIMICK
REDUCE BLOOD LEVELS OF GROWTH HORMONE AND IGF-I (SOMATOMEDIN C) IN ACROMEGALY PATIENTS
SYMPTOMATIC TREATMENT

INJECTION ORAL SUBCUTANEOUS

Cmax 5.1 NANOMOLAR (100 MICROGRAM)

VD 13.6 LITER

PPB 65 PERCENT

Cl 8.5 LITER / HOUR

HT 1.8 HOUR

SOMATOSTATIN RECEPTOR TYPE 1
SOMATOSTATIN RECEPTOR TYPE 5
SUBSTANCE-K RECEPTOR

SOMATOSTATIN RECEPTOR AGONIST CHEMBL2111436 SOMATOSTATIN RECEPTOR P30872 SOMATOSTATIN RECEPTOR TYPE 1 HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE SOMATOSTATIN RECEPTORANSM (in French)

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