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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CLORAZEPATE (has an active metabolite)

CLORAZEPATE


ATC N05BA05

NERVOUS SYSTEM
ANXIOLYTIC
ANTICONVULSANTS
GABA MODULATORS

ORAL

VD 13 LITER (65 KILOGRAM)

Cl 4.29 LITER / HOUR (65 KILOGRAM)

HT 2.4 HOUR

SOLUBILITY SOLUBLE IN WATER

GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT ALPHA-1 (GABA)

GABA-A receptor alpha-1,beta-2,gamma-2 UNIPROT P14867 GABRA1 -- GABA-A receptor alpha-2,beta-3,gamma-2 UNIPROT P18507 GABRG2

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