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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
METHANTHELINE DISCONTINUED

METHANTHELINE


ATC A03AB07

METABOLISM
ANTISPASMODIC
CHOLINERGIC RECEPTOR ANTAGONIST
TREATMENT OF OVERACTIVE BLADDER SYNDROME, HYPERSALIVATION AND HYPERHIDROSIS

ORAL

Cmax 73.5 NANOMOLAR (PMID22527350)

HT 2 HOUR

MUSCARINIC ACETYLCHOLINE RECEPTOR M1

HISTAMINE H2 RECEPTOR ANTAGONIST CHEMBL1941 HISTAMINE H2 RECEPTOR P25021 HISTAMINE H2 RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR HISTAMINE RECEPTORANSM (in French)

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