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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
LOMEFLOXACIN DISCONTINUED

LOMEFLOXACIN


ATC J01MA07
ATC S01AE04

ANTIBACTERIAL
ANTIINFECTIVE
INHIBITOR

ORAL

Cmax 9.1 MICROMOLAR (400 MG)

F 97 PERCENT

VD 97.3 LITER (EQN)

PPB 10 PERCENT

Cl 8.7 LITER / HOUR

HT 7.75 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

DNA GYRASE
DNA TOPOISOMERASE

BACTERIAL DNA GYRASE INHIBITOR CHEMBL2311224 BACTERIAL DNA GYRASE P0AES4 DNA GYRASE SUBUNIT A BACTERIA ENZYME ISOMERASEANSM (in French)

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