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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| BISOPROLOL
| BISOPROLOL |
CARDIOVASCULAR | ORAL | Cmax 0.21 MICROMOLAR (20 MG) Tmax 3 HOUR F 80 PERCENT VD 156 LITER (65 KILOGRAM) PPB 30 PERCENT Cl 14.4 LITER / HOUR (65 KILOGRAM) HT 10 HOUR SOLUBILITY SOLUBLE IN WATER | BETA-1 ADRENERGIC RECEPTOR ADRENERGIC BETA-2 RECEPTOR | Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 more at DrugCentral | EMA | |||
