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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
SUCCINYLCHOLINE

SUCCINYLCHOLINE


ATC M03AB01

METABOLISM
ULTRA SHORT-ACTING NEUROMUSCULAR DEPOLARIZING AGENTS
SKELETAL MUSCLE RELAXANTS
ADJUNCT TO GENERAL ANESTHESIA

INJECTION INTRAMUSCULAR INTRAVENOUS

VD 0.14 LITER (65 KILOGRAM)

Cl 250.2 LITER / HOUR

HT 0.07 HOUR (PMID14564614)

SOLUBILITY VERY SOLUBLE IN WATER

ACETYLCHOLINE RECEPTOR

PDB 2HA6 (CRYSTAL STRUCTURE OF MUTANT S203A OF MOUSE ACETYLCHOLINESTERASE COMPLEXED WITH SUCCINYLCHOLINE)

LIGAND CODE = SCK (link to the list of PDB complexes)

Download experimental 3D coordinates of SCK with added hydrogens

ION CHANNEL ACHA_HUMAN AGONIST P02708ANSM (in French)

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